Quarterly report pursuant to Section 13 or 15(d)

Business and Viability of Operations (Details Textual)

v3.19.1
Business and Viability of Operations (Details Textual)
1 Months Ended 3 Months Ended 12 Months Ended
Jul. 26, 2018
USD ($)
$ / shares
shares
Mar. 31, 2019
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Dec. 31, 2018
USD ($)
shares
Mar. 31, 2018
USD ($)
Jul. 23, 2010
shares
Stockholders' Equity, Reverse Stock Split     15-for-1      
Preferred Stock, Shares Authorized | shares     20,000,000      
Common Stock, Shares Authorized | shares   200,000,000 200,000,000 200,000,000    
Common Stock, Shares, Issued | shares   15,490,175 324,821 15,366,327   4,872,221
Preferred Stock, Shares Issued | shares 2,762,594   2,762,594     41,438,818
Retained Earnings (Accumulated Deficit)   $ (178,205,000)   $ (175,640,000) [1]    
Cash and Cash Equivalents, at Carrying Value   322,000 $ 249,000 $ 3,218,000 [1] $ 75,000  
Payments of Stock Issuance Costs   $ 900,000        
Convertible Preferred Stock, Shares Issued upon Conversion | shares 2,762,594          
Debt Instrument, Convertible, Number of Equity Instruments 9,527,144          
Repayments of Notes Payable $ 200,000          
IPO [Member]            
Shares Issued, Price Per Share | $ / shares $ 5.00          
Proceeds from Issuance of Common Stock $ 10,273,000          
Stock Issued During Period, Value, New Issues $ 12,000,000          
Stock Issued During Period, Shares, New Issues | shares 2,400,000          
Payments for Underwriters Discounts and Commissions $ 900,000          
Payments for Underwriters Accountable and Nonaccountable Expenses 220,000          
Payments of Stock Issuance Costs $ 607,000          
[1] The condensed consolidated balance sheet as of December 31, 2018 was derived from the audited consolidated balance sheet as of that date.